Mixed bacterial toxins in the treatment of tumors. II. Gross and microscopic changes produced in sarcoma 37 and in mouse tissues.

نویسندگان

  • A J DONNELLY
  • H F HAVAS
  • M E GROESBECK
چکیده

Mixed bacterial toxins have been used in an ef fort to destroy malignant tumors in patients and animals since 1892, when Coley (13) initiated clini cal applications. No systematic study of the histopathologic effects of mixed bacterial toxins on ex perimental tumors has been found. Several good studies of changes elicited in tumors by products from single bacterial strains have been published (3, 5, 17), but the specific investigation of changes produced by mixed bacterial toxins in tumors and hosts seemed warranted.

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عنوان ژورنال:
  • Cancer research

دوره 18 2  شماره 

صفحات  -

تاریخ انتشار 1958